Publications
Joshua Buse, Ildiko Badea, Ronald E. Verrall and Anas El-Aneed, 2010. Tandem Mass Spectrometric Analysis of the Novel Gemini Surfactant Nanoparticle Families C12-s and G18:1-s. Spectroscopy Letters, 43, 447-457.
McDonald Donkuru, Ildiko Badea, Shawn Wettig, Ronald Verrall, Mahmoud Elsabahy and Marianna Foldvari, 2010. Advancing nonviral gene delivery: lipid- and surfactant-based nanoparticle design strategies. Nanomedicine, 5,1103-1127.
Peng Yang, Jagbir Singh, Shawn Wettig, Marianna Foldvari, Ronald E. Verrall, Ildiko Badea, 2010. Enhanced gene expression in epithelial cells transfected with amino acid-substituted gemini nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics, 75, 311-320.
S. D. Wettig, R. E. Verrall, and M. Foldvari, 2008. Gemini Surfactants: A New Family of Building Blocks for Non-viral Gene Delivery Systems. Current Gene Therapy, 8, 9-23.
E. Blomberg, R. Verrall and P. Claesson, 2008. Interactions between Adsorbed Layers of Cationic Gemini Surfactants. Langmuir, 24, 1133-1140.
S. D. Wettig, I. Badea, M. Donkuru, R. E. Verrall, M. Foldvari, 2007. Structural and Transfection Properties of Amine-Substituted Gemini Surfactant-Based Nanoparticles. The Journal of Gene Medicine, 9, 649-658.
C. Wang, S. D. Wettig, M. Foldvari, and R. E. Verrall, 2007. Synthesis, Characterization, and Use of Asymmetric Pyrenyl-Gemini Surfactants as Emissive Components in DNA-Lipoplex Systems. Langmuir, 23, 8995-9001.
I. Badea, S. D. Wettig, R. Verrall, M. Foldvari, 2007.Topical Non-Invasive Gene Delivery Using Gemini Nonoparticles in Interferon-g-Deficient Mice. European Journal of Pharmaceutics and Biopharmaceutics, 65, 414-422.
C. Wang, X. Li, S. D. Wettig, I. Badea, M. Foldvari, and R. E. Verrall, 2007. Investigation of Complexes Formed by Interaction of Cationic Gemini Surfactants with Deoxyribonucleic Acid. Physical Chemistry Chemical Physics, 9, 1616-1628.
S. D. Wettig, C. Wang, R. E. Verrall and M. Foldvari, 2007. Thermodynamic and Aggregation Properties of Aza- and Imino-Substituted Gemini Surfactants Designed for Gene Delivery. Physical Chemistry Chemical Physics, 9, 871-877.
M. Foldvari, I. Badea, S. Wettig, R. Verrall and M. Bagonluri, 2006. Structural Characterization of Novel Gemini Non-viral DNA Delivery Systems for Cutaneous Gene Therapy. Journal of Experimental Nanoscience, 1, 165-176.
Research
Thermodynamic, dynamic and spectroscopic methods are being used to investigate amphiphilic systems that self-assemble or form strong complexes by means of noncovalent bonding. Micellar, surfactant-polymer and cyclodextrin-inclusate systems are being used to obtain improved information about their precise morphologies and mechanism of association in order to assess their potential as model systems for understanding some fundamental biological interactions. As well, photochemically prepared fluorophores are being evaluated as potential structural and conformational probes in the stereodynamic studies of nucleic acids.