News & Events
Chemistry Weekly Seminar - Professor Mark Stradiotto
Posted on 2017-10-16 in Events
Oct 27, 2017
Move Over Palladium: Developing PAd-DalPhos/Nickel-Catalysed C-N Cross-Couplings
The field of nickel-catalyzed C(sp2)-N cross-coupling has evolved in recent years such that current state-of-the-art nickel catalysts in many applications now rival or supersede the best palladium catalysts, in terms of both substrate scope and mild reaction conditions. This is due in large part to the development of broadly effective air-stable Ni(II) pre-catalysts including LNi(-aryl)halide complexes (L = phosphine or NHC). Our research group has recently developed the PAd-DalPhos ligand, and have shown that the derived complex (PAd-DalPhos)Ni(o-tolyl)Cl (see inset) is a superlative pre-catalyst for C(sp2)-N cross-couplings, encompassing a broad substrate scope with respect to both the amine (e.g., ammonia, alkylamines, and amides) and aryl electrophile coupling partners. The development of this catalytic chemistry, along with details of our on-going experimental and computational mechanistic investigations, will be the focus of this presentation.
 Lead publication: Stradiotto and co-workers: Nature Comm. 2016, 7, 11073.
Chemistry Special Seminar - Dr. Travis Dudding
Posted on 2018-05-25
Dr. Travis Dudding of Brock University will present a special seminar.
Chemistry Seminar - Theerawat Prasertanan
Posted on 2018-05-10
Theerawat Prasertanan, PhD candidate, will present a seminar.
Chemistry Special Seminar
Posted on 2018-03-29
Prof. Dr. Ingo Krossing of the University of Freiburg, Germany will present a special seminar.
Chemistry Special Seminar - Dr. Raymond J. Andersen
Posted on 2018-03-14
Dr. Raymond J. Andersen, University of British Columbia, will present a special seminar.
Chemistry Weekly Seminar - Dr. Martin St. Maurice
Posted on 2018-02-14
Martin St. Maurice of Marquette University will present a seminar.
Chemistry Weekly Seminar - Dr. Geoff Horsman
Posted on 2018-01-30
Dr. Geoff Horsman of Wilfrid Laurier University, will present a seminar.