Research Area(s)
- Neurodevelopment in C. elegans
- cilia genes
- Aging
- hypoxic stresss
- chromosome segregation
Publications
- R. Reed, J.N.Nyarko, D. D. Mousseau, C.E. de Carvalho (2023). A role of Shugoshin in human cilia? MicroPubl Biol 2:2023:10.17912/micropub.biology.001013. https://doi: 10.17912/micropub.biology.001013. eCollection 2023
- R. Reed, K. Park, B. Waddell, T. Timbers, C. Li, K. Baxi, R.M. Giacomin, M. Leroux an C.E. de Carvalho (2023). The Caenorhabditis elegans Shugoshin regulates TAC-1 in cilia. Sci Rep. https://doi.org/10.1038/s41598-023-36430-8
- M. O. Quartey, J.N.K. Nyarko, J. Maley, R.M. Heistad, K.J. Knudsen, P.R. Pennington, S.C. Leeary, M.A.C. Bolanos, J. Buttigieg, J.R. Barnes, M.P. Parsons, C.E. de Carvalho, and D.D. Mousseau (2021). The a-b(1-38) peptide is a negative modulator of the Alzheimer disease-related a-b (1-42) peptide. Sci Rep. https://doi.org/10.1038/s41598-020-80164-w
- R. Bowman, N. Balukoff, A. Clemons, E. Koury, K. Baxi, C.E. de Carvalho and S. Smolikove (2020). Akirin is required for muscle function and acts through the TGF-b Sma/Mab signaling pathway in C. elegans development". G3; 10: 387-400. https://doi.org/10.1534/g3.119.400377
- Ghavidel, K. Baxi, M. Prusinkiewicz, C. Swan, Z.R. Belak, C.H. Eskiw, T. Harkness and C.E. de Carvalho (2018). Rapid nuclear exclusion of Hcm1 in aging Saccharomyces cerevisae leads to vacuolar alkalinization and replicative senescence. G3; 8: 1579-1592. * co-corresponding authors. https://doi.org/10.1534/g3.118.200161
- K. Baxi and C.E. de Carvalho (2018). Assessing lysosomal alkanilization in the intestine of live C. elegans. J. Vis Exp. 134; doi: 10.3791/57414. https://doi.org/10.3791/57414
- K. Baxi, A. Ghavidel, Waddell, B., T. Harkness and C.E. de Carvalho (2017). Regulation of lysosomal function by the forkhead transcription factor DAF-16 couples reproduction to aging in Caenorhabditis elegans. Genetics 207; 83-101. https://doi.org/10.1534/genetics.117.204222
- Ghavidel, K. Baxi, C.E. de Carvalho and T. Harkness. (2015). A genome scale screen for mutants with delayed exit from mitosis: Ire1-independent induction of autophagy integrates ER homeostasis into mitotic lifespan. PLoS Genetics 11(8):e1005429. https://doi.org/10.1371/journal.pgen.1005429
- Y.B. Tzur, C.E. de Carvalho, I.V. Bolstelen, Y. Gu, I.M. Cheeseman and M. P. Colaiacovo. (2012). LAB-1 restricts Aurora B Kinase upon entrance into meiosis to promote the establishment and maintenance of sister chromatid cohesion. PLoS Biology 10(8):e1001378. https://doi.org/10.1371/journal.pbio.1001378
- N. Habibi-Babadi, A. Su, C.E. de Carvalho and A. Colavita. (2010). The N-glycanase png-1 acts cell non-autonomously to limit axon branching during organ formation in C. elegans. J. Neurosciences 30: 1766-1776. https://doi.org/10.1523/JNEUROSCI.4962-08.2010
Teaching & Supervision
I teach introductory genetics and senior genetics courses.
Education & Training
PhD. Molecular Genetics University of Alberta, Canada
MSc. Developmental Genetics Osaka University, Japan
BSc in Biological Science State University of Campinas, Brazil (with equivalency in Canada)