Welcome to The Bonham-Smith lab
Peta C. Bonham-Smith Ph.D.
Our lab primarily works on elucidating the role of ribosomal proteins in the function of the plant ribosome and the plant cell in general.
In Arabidopsis thaliana, we study the regulation of expression of ribosomal proteins as well as r-protein isoforms and ribosome heterogeneity.
Plant Molecular biology: Molecular biology of the plant ribosome and plant development.
(Anoop Sindhu [PDF], Prasad & Chad Stewart) Ribosomes are the celular machines found in ALL living cells that are responsible for the production of proteins, without which we can not live and function. Arabidopsis ribosomes are comprised of 81 proteins (coded by 254 genes in gene families of between 2-7 members) attached at specific locations to four ribosomal rRNAs, resulting in the two unequal (1 small and 1 large) subunit structure of the ribosome. Our research is involved in determining the role of ribosomal proteins in ribosome function and heterogeneity, and how expression of ribosomal proteins is regulated and coordinated.
Why would Arabidopsis need 900,000,000,000,000,000,000,000,000,000 possible combinations of ribosome?
TRICHOME DEVELOPMENT in ARABIDOPSIS AND BRASSICAS
(Ushan Alahakoon [co-supervisor, Dr. Margie Gruber, AAFC, Saskatoon]) Trichomes are hairs that grow out of some of the epidermal cells of plant leaves. We are interested in identifying the developmental pathway of trichome development in Brassicas, such that the information generated can be used to enhance trichome production in Brassicas and thereby increase plant resistance to insect feeding.